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Title: Development of gene expression fingerprints for identification of environmental contaminants using cDNA arrays
Authors: Inouye, Laura S.
Ang, Choo Yaw 1969-
McFarland, Victor A.
Keywords: Contaminated sediments
Gene expression
Dredging Operations and Environmental Research Program (U.S.)
Publisher: Engineer Research and Development Center (U.S.)
Series/Report no.: Technical Note (Dredging Operations and Environmental Research Program (U.S.)) ; no.ERDC TN-DOER-R4
Abstract: PURPOSE: This technical note reports the current status of work being done at the U.S. Army Engineer Research and Development Center (ERDC) to develop cDNA array-based assays that map gene expression from contaminant exposures. Results substantiate that distinct gene expression profiles exist for major contaminant classes such as PAHs, PCBs, and PCDD/Fs. Results also indicate that identification of these contaminant mixtures in environmental media is possible by examining their effects on gene expression in mammalian cells.
Description: Technical Note
Gov't Doc #: ERDC TN-DOER-R4
Rights: Approved for public release; distribution is unlimited
Appears in Collections:Technical Note

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