Abrasion testing of products containing nanomaterials, SOP-R-2 : Scientific Operating Procedure Series: Release (R)

Abstract

Abrasion is an important consideration for the potential release of nanoparticles during the service life of a nanotechnology. This SOP presents a general method for abrading a material using a rotating sample platform in contact with a weighted sandpaper fixture. Particles collected with this method are analyzed with a condensation particle counter (CPC) and a fast mobility particle sizer (FMPS), with additional particles collected on in-line filters for further analysis. The abrading process is carried out in a particle-free environment and released particles are moved by a defined airflow from the chamber to the collection/analysis apparatus. Particle release is monitored in real time by the CPC (10nm >1 μm) and FMPS (32 particle size bins from 5-550 nm), and further characterization of filter-collected particles can be accomplished post-testing.